After a young mother murders her family in her own house, a detective attempts to investigate the mysterious case, only to discover that the house is cursed by a vengeful ghost. Now targeted by the demonic spirits, the detective must do anything to protect herself and her family from harm.
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A young Japanese woman who holds the key to stopping the evil spirit of Kayako, travels to the haunted Chicago apartment from the sequel, to stop the curse of Kayako once and for all.
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In Pasadena, Mrs. Davis sends her daughter Aubrey Davis to Tokyo to bring her sister Karen Davis, who is interned in a hospital after surviving a fire, back to the USA. After their meeting, Karen dies and Aubrey decides to investigate what happened to her and gets herself trapped in the same situation, being chased by the ghost of the house. Meanwhile in Tokyo, the three high school mates Allison, Vanessa and Miyuki visit the famous haunted house and are also chased by the ghost. In Chicago, Trish moves to the apartment of her boyfriend Bill, who lives with his children, the teenager Lacey and boy Jake. On the next door, weird things happen with their neighbor.
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Karen Davis, an American Nurse, moves to Tokyo and encounters a supernatural spirit who is vengeful and often possesses its victims. A series of horrifying and mysterious deaths start to occur, with the spirit passing its curse onto each victim. Karen must now find away to break this spell, before she becomes its next victim.
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